https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Prostate-specific membrane antigen PET-CT in patients with high-risk prostate cancer before curative-intent surgery or radiotherapy (proPSMA): a prospective, randomised, multicentre study https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:41947 Wed 22 Mar 2023 14:31:19 AEDT ]]> Methylation diet and methyl group genetics in risk for adenomatous polyp occurrence https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:28251 Wed 11 Apr 2018 14:22:59 AEST ]]> Vitamin D, folate, and potential early lifecycle environmental origin of significant adult phenotypes. https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18545 Wed 11 Apr 2018 12:52:16 AEST ]]> An optimised aqueous extract of phenolic compounds from bitter melon with high antioxidant capacity https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19234 Wed 11 Apr 2018 12:22:00 AEST ]]> Development of biodegradable films based on seaweed polysaccharides and Gac pulp (Momordica cochinchinensis), the waste generated from Gac oil production https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:39154 Momordica cochinchinensis) is a tropical fruit. It belongs to the Cucurbitaceae family. Gac pulp (or mesocarp) that accounts for 40-50% of fruit weight is commonly discarded during the processing of Gac fruit. However, this by-product is a rich source of nutrients and bioactive compounds, which are potential to produce edible films. This study aimed to determine the effect of sodium alginate, kappa-carrageenan, Gac pulp and glycerol on film properties and optimise the formula of this composite film for further applications using a response surface methodology (RSM). The results showed that sodium alginate, kappa-carrageenan, Gac pulp, and glycerol affected physical and barrier properties, colour parameters, and mechanical properties of the films. The optimal formulation to generate a composite film from Gac pulp include sodium alginate 1.03%, kappa-carrageenan 0.65%, Gac pulp 0.4%, and glycerol 0.85% (w/v), where this film produces high mechanical properties, low water vapour permeability and acceptable physical properties. This optimised film formulation demonstrates a potential for food application.]]> Thu 19 May 2022 16:15:35 AEST ]]> Folate nutritional genetics and risk for hypertension in an elderly population sample https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:6997 T-MTHFR, 1298A>C-MTHFR, 80G>A-RFC, 2756A>G-MS, 66A>G- MSR, 19bpDHFR and 1561C>T-GCPII), only 677C>T-MTHFR was a significant risk for hypertension: OR 1.89; 95% CI 1.07–3.32 (χ² p = 0.038). Additionally, hypertensive subjects had a significantly lower intake of dietary folate than normotensive individuals (p = 0.0221), although this did not markedly alter blood metabolite levels. Several significant linear associations between dietary folate and related blood metabolites were found in normotensive subjects (p<0.001 for Hcy, red cell and serum folate) and were as predicted on an a priori basis – generally weaker associations existed in hypertensive subjects (p<0.05 for serum folate). This was true for data examined collectively or by genotype. Multiple regression analysis for diastolic or systolic blood pressure showed significant interaction for gender and folate intake (p = 0.014 and 0.019, respectively). In both cases this interaction occurred only in females, with higher folate intake associated with decreased blood pressure. Regressing diastolic blood pressure and 677C>T-MTHFR genotype showed significance (males; p = 0.032) and borderline significance (all subjects). Conclusion: Dietary folate and 677C>T-MTHFR genotype may modify blood pressure.]]> Sat 24 Mar 2018 08:37:49 AEDT ]]> Hydrogen sulphide-related thiol metabolism and nutrigenetics in relation to hypertension in an elderly population https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18190 Sat 24 Mar 2018 08:04:22 AEDT ]]> Vitamin C-related nutrient-nutrient and nutrient-gene interactions that modify folate status https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:17304 Sat 24 Mar 2018 08:01:49 AEDT ]]> TAS2R38 bitter taste genetics, dietary vitamin C, and both natural and synthetic dietary folic acid predict folate status, a key micronutrient in the pathoaetiology of adenomatous polyps https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:17921 Sat 24 Mar 2018 07:56:14 AEDT ]]> Preliminary evidence for genetic selection of 677T→MTHFR by natural annual cycle of folate abundance https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:4945 Sat 24 Mar 2018 07:48:07 AEDT ]]>